Figure 1.
Model of Tinnitus-Hyperacusis network: (A) High-dose SS induces hyperactivity and increases functional connectivity in an auditory network consisting of AC, MGB and IC (thin dashed line) and emotional network linking the amygdala (AMY) with the AC (thick dashed line). The hyperactivity and enhanced functional connectivity are also occurred in the PFL and RF, areas outside the classical auditory pathway but connected to the AC. (B) SS increases the functional coupling between the AC and the two regions outside the classical auditory pathway, the PFL and RF (PnC).