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Real-time relationship of patient's physiological parameters with acute brain injury. (A) As ICP plateau waves occur (arrows), simultaneous drops in CPP below 60 mmHg and PbtO2 below 15 mmHg were observed. Microdialysis data consistently showed elevated LRP but consistent decrease in brain glucose levels occurred after each plateau wave, suggesting metabolic disturbance after brain hypoxia secondary to cerebral flow failure.
