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. 2017 May 7;2017:3679295. doi: 10.1155/2017/3679295

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Copyright © 2017 Xinwen Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Time course of the suppressive effects of TJ-20 on the clinical parameters of AA rats. AA rats were given TJ-20 according to schedule I (filled triangles), II (open squares), or III (open triangles) or given distilled water (closed circle) orally once a day after adjuvant injection (AA rats). Rats injected with mineral oil alone and given TJ-20 (open circle) served as controls. The hind paw swelling (a) and body weight gain (b) were measured at 1-week intervals. TJ-20 administered according to schedules I and II significantly ameliorated the progression of AA. Data are the mean ± SD for 6 rats in each group. Asterisks indicate a statistically significant difference from AA rats (^∗P < 0.05, ^∗∗P < 0.01).