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. Author manuscript; available in PMC: 2017 Jun 7.
Published in final edited form as: J Allergy Clin Immunol. 2016 Nov 19;139(6):1897–1905.e1. doi: 10.1016/j.jaci.2016.10.018

Fig 4.

Fig 4

mCyp c 1–specific rabbit antiserum inhibits rCyp c 1–induced basophil degranulation in vitro and Cyp c 1–induced allergic symptoms in vivo. A, Rat basophil leukemia cells were loaded with pooled sera from rCyp c 1–sensitized mice in the presence or absence of mCyp c 1–specific rabbit antiserum or control antiserum (x-axis). The percentage of total β-hexosaminidase release is displayed on the y-axis (triplicates ± SD). B, Significant (**P < .01) suppression of allergic symptoms in Cyp c 1–sensitized mice by mCyp c 1–specific rabbit antiserum after challenge with Cyp c 1. Allergic symptoms (y-axis: mean symptom scores ± SD) in Cyp c 1–sensitized mice having received mCyp c 1–specific or control antiserum (x-axis).