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. Author manuscript; available in PMC: 2017 Jun 7.
Published in final edited form as: J Allergy Clin Immunol. 2016 Nov 19;139(6):1897–1905.e1. doi: 10.1016/j.jaci.2016.10.018

Fig 6.

Fig 6

Suppression of Cyp c 1–induced basophil degranulation and allergic symptoms with a mCyp c 1–specific mouse antiserum. A, Rat basophil leukemia cells loaded with pooled sera from rCyp c 1–sensitized mice (day 43) were challenged with rCyp c 1 in the presence or absence of mCyp c 1–specific mouse antiserum or control hP62 (a recombinant grass pollen hypoallergen)–specific antiserum (x-axis). The percentage of total ß-hexosaminidase release is displayed on the y-axis (triplicates ± SD). B, Allergic symptoms (y-axis: mean symptom scores ± SD) of carp extract-sensitized mice treated with either mouse α-mCyp c 1 serum or mouse α-hP62 serum or of untreated mice (x-axis) after challenge with carp extract (*P < .05; **P < .01).