Figure 4. Immunohistochemical studies.
(a) H&E, anti–mouse-CD31 and anti–human-TF (CD142) staining of healthy and metastatic lungs (Scale bars = 2 mm). (b) Direct comparison of BLI, Raman map of αTF-SERRS-NPs, and 3D H&E in a mouse with breast cancer lung metastases. Note the high degree of correlation between the Raman map, BLI, and 3D histology.