Table 3.
MIC and MBC of antifungal agents compounded into denture adhesive for C. albicans ATCC 6412 and HMV4C. MIC and MBC values in each row with the same letter are not significantly different (p < 0.05).
| Test | ATCC 64124 (1% adhesive) | ATCC 64124 (water) | HMV4C (1% adhesive) | HMV4C (water) |
|---|---|---|---|---|
| Amphotericin B | ||||
| MIC | 50.0 (0.0)a | 3.1 (0.0)b | 50.0 (0.0)a | 1.6 (0.0)c |
| MBC | 50.6 (0.4)a | 2.6 (0.5)b | 50.3 (0.0)a | 2.6 (0.5)b |
| Chlorhexidine dihydrochloride | ||||
| MIC | 3.1 (0.0)a,b | 1.3 (0.3)b | 9.4 (3.1)a | 3.1 (0.0)a,b |
| MBC | 3.1 (0.0)b | 1.3 (0.3)b | 10.4 (2.08)a | 3.1 (0.0)b |
| Chlorhexidine gluconate | ||||
| MIC | > 50.0 (0.0)a | 6.3 (0.0)c | > 50.0 (0.0)a | 12.5 (0.0)b |
| MBC | > 50.0 (0.0)a | 6.3 (0.0)c | > 50.0 (0.0)a | 12.5 (0.0)b |
| Fluconazole | ||||
| MIC | > 50.0 (0.0)a | > 50.0 (0.0)b | 0.1 (0.0)a | 0.1 (0.0)b |
| MBC | > 50.0 (0.0)a | > 50.0 (0.0)a | 0.1 (0.0)b | 0.1 (0.0)b |
| Nystatin | ||||
| MIC | > 50.0 (0.0)a | 3.1 (0.0)b | 50.0 (0.0)a | 2.6 (0.5)b |
| MBC | 0.01 (0.0)c | 3.1 (0.0)b | 50.0 (0.0)a | 3.1 (0.0)b |
MIC, minimal inhibitory concentrations
Shown are the mean μg/ml (standard error) values