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. 2017 May;56(3):273–289.

Table 2.

Average number of A. tetrapteraova by fecal centrifugation flotation per cage and average number of A. tetrapteraworms per mouse at necropsy in CrTac:NCr-Foxn1nunude mice inoculated with A. tetrapteraova via oral gavage or topically and then treated with different anthelmintic drugs for 8 wk

Method of inoculation of ova Treatment Group n Average no. of ova after treatment
Average no. (range) of worms at necropsy
Week 1 Week 2 Week 3 Week 4
Oral gavage NEG 3 0 0 0 0 0 (0)
POS 6 3 8 9 29 58 (5–110)
FEN 11 0 0 0 0 0 (0)
FEN + PIP 11 0 0 0 0 0 (0)
PIPW 7 0 0 0 0 0 (0)
Topical POS 8 26 99 46 5 107 (2–144)
FEN 8 0 0 0 0 0 (0)
FEN + PIP 12 0 0 0 0 0 (0)
PIPW 7 0 0 0 0 0 (0)

FEN, 150 ppm fenbendazole in feed; FEN + PIP, 150 ppm fenbendazole and 5 ppm piperazine in feed; NEG, negative-control mice that were inoculated with distilled water only; PIPW, 2.1 mg/mL piperazine in drinking water; POS, positive-control mice that were inoculated with A. tetraptera ova but were not treated.