Table 2.
Method of inoculation of ova | Treatment Group | n | Average no. of ova after treatment |
Average no. (range) of worms at necropsy | |||
Week 1 | Week 2 | Week 3 | Week 4 | ||||
Oral gavage | NEG | 3 | 0 | 0 | 0 | 0 | 0 (0) |
POS | 6 | 3 | 8 | 9 | 29 | 58 (5–110) | |
FEN | 11 | 0 | 0 | 0 | 0 | 0 (0) | |
FEN + PIP | 11 | 0 | 0 | 0 | 0 | 0 (0) | |
PIPW | 7 | 0 | 0 | 0 | 0 | 0 (0) | |
Topical | POS | 8 | 26 | 99 | 46 | 5 | 107 (2–144) |
FEN | 8 | 0 | 0 | 0 | 0 | 0 (0) | |
FEN + PIP | 12 | 0 | 0 | 0 | 0 | 0 (0) | |
PIPW | 7 | 0 | 0 | 0 | 0 | 0 (0) |
FEN, 150 ppm fenbendazole in feed; FEN + PIP, 150 ppm fenbendazole and 5 ppm piperazine in feed; NEG, negative-control mice that were inoculated with distilled water only; PIPW, 2.1 mg/mL piperazine in drinking water; POS, positive-control mice that were inoculated with A. tetraptera ova but were not treated.