Fig. 8.

Correlation between mEPSC amplitude and decay kinetics in untreated and treated euploid and Ts65Dn mice. Scatter plots of mEPSC τdec, obtained by fitting the decay phase of average mEPSCs with a single mono-exponential function, as a function of peak mEPSC amplitude in untreated euploid (A) and Ts65Dn (B) mice and euploid (C) and Ts65Dn (D) mice treated with ELN. Data derive from 9 untreated euploid mice (11 cells), 7 untreated Ts65Dn mice (18 cells), 8 ELN-treated euploid mice (9 cells), and 4 ELN-treated Ts65Dn mice (5 cells).