Table 3.
OPV coverage during each round of supplementary immunisation activities
| Control (Arm A) |
Community mobilisation and health camps (arm B) |
Community mobilisation and health camps and IPV (arm C) |
p value* | ||||
|---|---|---|---|---|---|---|---|
| Estimated coverage | Estimated coverage | Coverage difference (95% CI) | Estimated coverage | Coverage difference (95% CI) | |||
| Round 1 | |||||||
| Karachi | 63% (53 to 71) | 81% (74 to 87) | 18·6% (7·2 to 30·1) | 75% (66 to 82) | 12·3% (−0·2 to 24·9) | 0·0072 | |
| Bajaur | 77% (74 to 80) | 79% (77 to 82) | 1·9% (−1·9 to 5·7) | 81% (78 to 83) | 3·5% (−0·4 to 7·4) | 0·21 | |
| Kashmore | 72% (73 to 74) | 76% (74 to 78) | 3·7% (1·0 to 6·4) | 78% (76 to 80) | 5·4% (2·9 to 7·9) | 0·0002 | |
| Total | 71% (68 to 74) | 78% (76 to 80) | 6·6% (3·5 to 9·7) | 78% (76 to 80) | 6·6% (3·4 to 9·8) | <0·0001 | |
| Round 2 | |||||||
| Karachi | 72% (65 to 79) | 80% (74 to 84) | 7·4% (−1·4 to 16·2) | 84% (80 to 88) | 12·0% (3·8 to 20·1) | 0·0142 | |
| Bajaur | 76% (73 to 78) | 83% (80 to 85) | 6·9% (3·4 to 10·1) | 84% (81 to 86) | 7·7% (4·3 to 11·2) | <0·0001 | |
| Kashmore | 75% (72 to 77) | 80% (77 to 82) | 5·2% (2·2 to 7·0) | 82% (78 to 84) | 7·0 (3·5 to 10·4) | 0·0001 | |
| Total | 75% (73 to 76) | 81% (79 to 83) | 6·2% (3·6 to 8·8) | 83% (81 to 85) | 8·4% (5·8 to 11·0) | <0·0001 | |
| Round 3 | |||||||
| Karachi | 77% (67 to 84) | 82% (78 to 86) | 5·5% (−4·0 to 14·9) | 88% (84 to 90) | 10·8% (1·9 to 19·8) | 0·0167 | |
| Bajaur | 77% (75 to 80) | 86% (84 to 88) | 8·3% (5·5 to 11·1) | 87% (84 to 89) | 9·2% (5·4 to 13·0) | <0·0001 | |
| Kashmore | 79% (75 to 82) | 82% (81 to 84) | 3·6% (0·0 to 7·2) | 85% (83 to 86) | 5·8% (2·2 to 9·5) | 0·0054 | |
| Total | 78% (75 to 80) | 83% (82 to 85) | 5·3% (2·3 to 8·2) | 86% (84 to 87) | 7·9% (5·0 to 10·8) | <0·0001 | |
| Round 4 | |||||||
| Karachi | 73% (68 to 77) | 82% (74 to 87) | 8·6% (1·1 to 16·1) | 86% (83 to 89) | 13·1% (7·8 to 18·5) | <0·0001 | |
| Bajaur | 81% (78 to 83) | 88% (86 to 90) | 6·9% (3·8 to 10·0) | 90% (88 to 91) | 8·6% (5·6 to 11·7) | <0·0001 | |
| Kashmore | 76% (74 to 78) | 86% (84 to 87) | 9·5% (6·9 to 12·2) | 87% (85 to 89) | 11·1% (8·3 to 13·9) | <0·0001 | |
| Total | 77% (75 to 79) | 85% (83 to 87) | 8·3% (6·0 to 10·6) | 88% (86 to 89) | 10·7% (8·7 to 12·6) | <0·0001 | |
| Overall (all sites, all rounds) | 75% (74 to 77) | 82% (81 to 83) | 6·6% (4·8 to 8·3) | 84% (83 to 85) | 8·5% (6·8 to 10·1) | <0·0001 | |
OPV=oral polio vaccine.
*
Testing the null hypothesis of no differences in coverage across the three arms. Numbers in parantheses are 95% CI.