Table 2.
Univariate analysis of the correlation between demographic and clinicopathological characteristics and survival time in patients with MM.
Characteristics | n | OS (mean) | PFS (mean) | |
---|---|---|---|---|
Age | ≥60 | 100 | 20.355 | 16.595 |
<60 | 81 | 28.233 | 20.102 | |
Gender | Male | 114 | 23.614 | 18.322 |
Female | 67 | 24.333 | 17.897 | |
Ig isotype | IgG | 97 | 22.531 | 16.210 |
IgA | 47 | 24.419 | 19.674 | |
Light chain | 31 | 21.914 | 18.971 | |
Others | 6 | 51.645 | 33.772 | |
ISS staging | I | 31 | 29.096 | 22.806 |
II | 86 | 28.490 | 21.231 | |
III | 64 | 15.161 | 11.796 | |
ECOG | 0-1 | 153 | 25.098 | 18.830 |
2–4 | 28 | 17.230 | 14.531 | |
Plt (×109/L) | ≥100 | 156 | 25.251 | 19.403 |
<100 | 25 | 15.327 | 10.440 | |
Hb (g/L) | ≥100 | 55 | 22.732 | 21.187 |
<100 | 126 | 26.511 | 16.846 | |
Scr (μmol/L) | ≥177 | 39 | 13.888 | 10.382 |
<177 | 142 | 26.625 | 20.302 | |
Serum Alb (g/L) | ≥35 | 49 | 25.292 | 20.049 |
<35 | 132 | 23.357 | 17.465 | |
Serum β2-MG (μmol/L) | ≥5.5 | 64 | 15.161 | 11.796 |
<5.5 | 117 | 28.650 | 21.648 | |
Serum LDH (IU/L) | ≥245 | 28 | 18.717 | 14.700 |
<245 | 153 | 24.826 | 18.799 | |
Serum Ca (mmol/L) | ≥2.75 | 21 | 13.268 | 11.910 |
<2.75 | 160 | 25.273 | 18.986 | |
Bortezomib | Yes | 111 | 24.816 | 18.957 |
No | 70 | 22.398 | 16.909 | |
Thalidomide | Yes | 144 | 26.712 | 20.368 |
No | 37 | 12.860 | 9.590 | |
Blood transfusion | Yes | 68 | 22.376 | 14.998 |
No | 113 | 24.786 | 20.070 |