Table 1. Breast cancer cell lines characterizations.
Cell line | ATCC no. | Medium | Subtype | Tumor type | ER | PgR | Her-2 | TP53 | RB1 |
---|---|---|---|---|---|---|---|---|---|
MCF-7 | HTB-22 | EMEM | L | Met AC | + | + | − | WT | WT |
T47D | HTB-133 | McCoys | L | IDC | + (low) | + (high) | − | GOF Mutation (L194F) Homozygous | WT |
HTB-122 | BT-549 | RPMI | B | IDC | − | − | − | GOF Mutation (R249S) Homozygous | Frameshift (c.265_607-del343) Homozygous |
CRL2324 | HCC1395 | RPMI | B | DC | − | − | − | GOF Mutation (R175H) Homozygous | WT |
Abbreviations: B, Basal B subtype; L, luminal subtype; DC, ductal carcinoma; IDC, invasive ductal carcinoma; Met AC, metastatic adenocarcinoma.