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. 2017 May 22;6:12. doi: 10.1186/s40035-017-0082-8

Fig. 2.

Fig. 2

MANF inhibited 6-OHDA-induced apoptosis in SHSY-5Y cells. a Representative fluorescent images for DAPI and TUNEL merged images in control group; SHSY-5Y cells treated with 150 μM 6-OHDA; SHSY-5Y cells treated with 150 μM 6-OHDA + 4 μg/mL MANF; b: The treatment of MANF showed a significant protective effect against 6-OHDA toxicity. Values represent means ± SEM, ***p < 0.001, one-way ANOVA with Bonferroni post test