Table 1.

Chararacteristics of acute pancreatitis cases and control subjects

	Acute ancreatitis
	Control subjects N = 27032		Cases N = 7577
Variable	n	(%)	n	(%)	P value*
Sex					0.42
Female	9072	33.6	2505	33.1
Male	17960	66.4	5072	66.9
Age group (year)					0.33
20-39	8149	30.2	2351	31.0
40-64	13055	48.3	3617	47.7
65-84	5828	21.6	1609	21.2
Age (year), mean (standard deviation)†	50.3	15.7	50.1	15.7	0.39
Etodolac					0.004
Never used	27016	99.94	7564	99.82
Active use	5	0.02	7	0.09
Non-active use	11	0.04	6	0.08
Other cyclooxygenase-2 inhibitors					< 0.001
Never used	21490	79.5	5628	74.3
Have used	5542	20.5	1949	25.7
Comorbidities before index date
Alcohol-related disease	119	0.44	339	4.47	< 0.001
Biliary stone	570	2.11	1563	20.6	< 0.001
Cardiovascular disease	4859	18.0	1885	24.9	< 0.001
Chronic kidney disease	481	1.78	322	4.25	< 0.001
Chronic obstructive pulmonary disease	3400	12.6	1176	15.5	< 0.001
Diabetes mellitus	2794	10.3	1509	19.9	< 0.001
Hepatitis B	584	2.16	316	4.17	< 0.001
Hepatitis C	275	1.02	188	2.48	< 0.001
Hypertriglyceridemia	4701	17.4	2252	29.7	< 0.001

Data are presented as the number of subjects in each group, with percentages given in parentheses, or the mean with standard deviation given in parentheses.

^* Chi-square test and

^† t-test comparing subjects with and without acute pancreatitis.