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. 2017 Feb 4;64(8):1066–1073. doi: 10.1093/cid/cix042

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© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Clinical and microbiological dynamics for participants challenged with Salmonella Typhi and Salmonella Paratyphi A. A, Pattern of blood culture results (red, positive; gray, negative; white, sample not collected). Numbers in parentheses refer to quantitative blood culture colony count (colony-forming units/mL) taken immediately prior to antibiotic treatment and correspond to day of treatment initiation. B, Pattern of stool shedding following challenge. Colored squares indicate stool culture results for S. Paratyphi A or S. Typhi (brown, positive; gray, negative; white, sample not collected). C, Maximum temperature (temp., °C) measurements by day. Abbreviations: day 0, day of challenge; nPD1–20, paratyphoid disease not diagnosed; nTD1–16, typhoid disease not diagnosed; PD1–20, confirmed paratyphoid disease; TD1–25, confirmed typhoid disease; Tx, day of treatment initiation.