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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2016 Sep 16;43(5):461–479. doi: 10.1007/s10928-016-9490-0

Fig. 4.

Fig. 4

Heat maps visualizing the effect of the competitive (EmaxAB = 2) Eq. (18), summation (EmaxAB = 3) Eq. (39), and stimulation (EmaxAB = 5) Eq. (43) CET are shown. Brighter color denotes a higher combination effect. The single maximal effects were set to EmaxA = 2 and EmaxB = 1 (Color figure online)

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