Table 1.
Participant characteristics at EDIC baseline stratified by occurrence of a cardiovascular event during follow-up
| Characteristics | All participants (n = 1,306) | Cardiovascular event |
||
|---|---|---|---|---|
| Yes (n = 155) | No (n = 1,151) | P value* | ||
| Age (years) | 35.5 ± 6.9 | 39.1 ± 6.1 | 35.1 ± 6.9 | <0.001 |
| Female sex | 623 (47.7) | 80 (51.6) | 543 (47.2) | 0.30 |
| White race | 1,257 (96.3) | 149 (96.1) | 1,108 (96.3) | 0.91 |
| Intensive group | 655 (50.2) | 71 (45.8) | 584 (50.7) | 0.25 |
| Primary cohort | 652 (49.9) | 58 (37.4) | 594 (51.6) | <0.001 |
| Duration of diabetes (years) | 13.5 ± 4.9 | 14.5 ± 5.2 | 13.3 ± 4.8 | 0.013 |
| Current cigarette smokers | 245 (18.8) | 41 (26.5) | 204 (17.7) | 0.009 |
| Current use of blood pressure medications | 118 (9.0) | 24 (15.5) | 94 (8.2) | 0.003 |
| Current use of lipid-lowering medications | 29 (2.2) | 7.7 (12) | 1.5 (17) | <0.001 |
| Albuminuria (ever) | 226 (17.3) | 43 (27.7) | 183 (15.9) | <0.001 |
| Weighted means from DCCT | ||||
| BMI (kg/m2) | 25.1 ± 3.1 | 25.7 ± 3.6 | 25.1 ± 3.0 | 0.11 |
| Systolic blood pressure (mmHg) | 115 ± 8 | 118 ± 9 | 115 ± 8 | <0.001 |
| Diastolic blood pressure (mmHg) | 74 ± 6 | 76 ± 5 | 74 ± 5 | <0.001 |
| HbA1c (%) | 8.14 ± 1.34 | 8.46 ± 1.47 | 8.09 ± 1.32 | 0.005 |
| HDL cholesterol (mg/dL) | 52 ± 12 | 51 ± 12 | 52 ± 12 | 0.67 |
| Non-HDL cholesterol (mg/dL) | 130 ± 30 | 144 ± 30 | 128 ± 29 | <0.001 |
| LDL cholesterol (mg/dL) | 114 ± 26 | 126 ± 26 | 112 ± 26 | <0.001 |
| Total cholesterol (mg/dL) | 182 ± 29 | 195 ± 31 | 180 ± 29 | <0.001 |
| Triglyceride (mg/dL) | 81 ± 38 | 92 ± 43 | 79 ± 37 | <0.001 |
Data are n (%) for categorical variables and mean ± SD for continuous variables.
*P values are based on the χ2 test for categorical variables and the Wilcoxon rank sum test for continuous variables.