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PrPC upregulates hemin-mediated synthesis of Hb in K562 cells. A) Red color of Hb is more evident in cell pellets of PrPC-expressing K562 cells (arrowhead) relative to non-transfected, vector, and PrPΔ51-89-expressing cells. B) Staining with benzidine confirms significantly more Hb in PrPC-expressing cells relative to vector controls (panel 1 versus 2, arrowhead).
