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. Author manuscript; available in PMC: 2018 Feb 20.
Published in final edited form as: Chem Res Toxicol. 2016 Dec 15;30(2):657–668. doi: 10.1021/acs.chemrestox.6b00394

Figure 8.

Figure 8

Correlation between DNA adducts levels derived from AαC and the relative abundance of AαC-HN2-O-Gluc formed in human hepatocytes. Relative abundance of AαC-HN2-O-Gluc (A) and dG-C8-AαC (B) formed in human hepatocytes. Cells were pre-treated with furafylline (5 μM) for 24h prior to incubation with 0.1, 1, 10 and 50 μM of AαC for 24h and the relative abundance of AαC-HN2-O-Gluc and dG-C8-AαC levels derived from AαC formed were estimated by mass spectrometry. (Student's t-test, * P<0.05; **P<0.01, ***P<0.005 versus control).