Table 3.
Distribution of Gender and Psychiatric Comorbidities with Odds Ratios in the At-Risk for Obsessive-Compulsive Disorder and Unaffected Control Groups
| Variables | At-risk for OCD (9.7%) n = 244 | Unaffected controls (90.3%) n = 2268 | OR | 95% CI | p |
|---|---|---|---|---|---|
| Psychiatric disorder (at least 1) | 61.07% | 22.18% | 5.50 | 4.14–7.33 | <0.0001 |
| Anxiety disorders | 30.33% | 6.83% | 5.93 | 4.25–8.24 | <0.0001 |
| Separation anxiety | 13.93% | 1.68% | 9.5 | 5.66–15.84 | <0.0001 |
| Specific phobia | 8.61% | 3% | 3.04 | 1.74–5.14 | <0.0001 |
| Social phobia | 2.87% | 0.84% | 3.5 | 1.23–8.79 | <0.0001 |
| GAD | 10.25% | 0.97% | 11.65 | 6.18–22.03 | <0.0001 |
| Mood disorders | 14.75% | 1.76% | 9.64 | 5.82–15.86 | <0.0001 |
| Major depression (MDD) | 14.75% | 1.63% | 10.44 | 6.25–17.36 | <0.0001 |
| ADHD | 22.95% | 9.61% | 2.80 | 1.97–3.93 | <0.0001 |
| Disruptive disorders | 15.57% | 5.86% | 2.96 | 1.95–4.41 | <0.0001 |
| ODD | 11.07% | 4.59% | 2.59 | 1.59–4.09 | <0.0001 |
| Conduct disorders | 5.33% | 1.19% | 4.67 | 2.18–9.51 | <0.0001 |
| Eating disorders | 1.64% | 0.26% | 6.28 | 1.29–26.67 | 0.011 |
| Tic disorder | 3.28% | 0.49% | 6.95 | 2.40–19.17 | <0.0001 |
| Others (grouped) | 3.69% | 0.44% | 8.65 | 3.07–23.89 | <0.0001 |
At-risk for OCD group: Determined by cutoff score 5 on OCS-CBCL; GAD: generalized anxiety disorder; MDD: major depressive disorder; ADHD: attention-deficit/hyperactivity disorder; ODD: Oppositional defiant disorder; others: Includes pervasive developmental disorder, stereotypic behavior, psychosis, and selective mutism grouped.
CI, confidence interval; OCD, obsessive-compulsive disorder; OR, odds ratios.