Fig. 5.

Effects of TNFα and various inhibitors on NO release from BAECs. BAECs were incubated for 4 h without (Control) and with TNFα and with the addition or lack of addition of the indicated inhibitors. Culture medium was then replaced with fresh medium containing the same additions. After a further 1 h incubation, nitrite accumulation in the conditioned medium was measured with an NO-specific chemiluminescence analyzer. Results shown are means ± S.E. for 3 separate experiments performed with each inhibitor.