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. 2017 May 1;33(5):410–423. doi: 10.1089/aid.2016.0204

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© Chitraporn Karnasuta et al. 2017; Published by Mary Ann Liebert, Inc.

This article is available under the Creative Commons License CC-BY-NC (http://creativecommons.org/licenses/by-nc/4.0). This license permits non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. Permission only needs to be obtained for commercial use and can be done via RightsLink.

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FIG. 3. — IgG antibodies to the gD peptide from RV144 and VAX samples. RV144 (red symbols), VAX003 (blue symbols), and VAX004 (green symbols) at 2 weeks post second AIDSVAX vaccination from visits 8 and A05, respectively. (A) Symbols are GMTs showing absorption of IgG antibodies binding to the gD peptide with 95% confidence intervals. Numbers indicate GMTs before (solid symbols) or after absorption (hollow symbols) of the gD binding antibodies. (B) IgG specificity to gD after multiple immunizations in VAX004 serum samples from second (visit A04), fourth (visit A08), and sixth (visit A12) AIDSVAX B/B vaccinations. Solid symbols show sera before absorption and hollow symbols show absorbed sera with the gD peptide. Recombinant gp120 CRF01_AE A244gD was the capturing antigen. The plots are means with standard deviations at absorbance 405 nm. x-axis shows visits. Numbers under x-axis show percentage of positive samples (A405 ≥ 0.25) and responses above dotted line are considered positive. **p < .01; ***p < .001; ****p < .0001.