Table 2. Association of BMI and WHR with total mortality and recurrence/disease-specific mortality among TNBC.
| Total mortality | Recurrence/disease-specific mortality | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Total | No. of Event | HR (95%CI)a | Total | No. of Event | HR (95%CI)a | |
| BMI at 1 year before diagnosis | ||||||
| < 18.5 | 25 | 6 | 1.15(0.47,2.8) | 25 | 5 | 1.26(0.48,3.27) |
| 18.5-23.9 | 271 | 56 | 1.00 | 271 | 52 | 1.00 |
| 24.0-27.9 | 160 | 44 | 1.20(0.79,1.82) | 160 | 35 | 1.23(0.78,1.94) |
| ≥ 28.0 | 62 | 22 | 1.79(1.06,3.03) | 62 | 20 | 1.83(1.05,3.21) |
| BMI at diagnosis | ||||||
| <18.5 | 30 | 8 | 1.16(0.54,2.50) | 30 | 7 | 1.28(0.57,2.89) |
| 18.5-23.9 | 279 | 60 | 1.00 | 279 | 53 | 1.00 |
| 24.0-27.9 | 152 | 43 | 1.19(0.79,1.81) | 152 | 36 | 1.38(0.88,2.17) |
| ≥ 28.0 | 57 | 17 | 1.36(0.78,2.40) | 57 | 16 | 1.53(0.84,2.77) |
| BMI at 6 months after diagnosis (baseline) | ||||||
| <18.5 | 17 | 3 | 0.80(0.25,2.61) | 17 | 2 | 0.53(0.13,2.22) |
| 18.5-23.9 | 253 | 56 | 1.00 | 253 | 50 | 1.00 |
| 24.0-27.9 | 183 | 49 | 1.21(0.81,1.80) | 183 | 42 | 1.15(0.75,1.77) |
| ≥ 28.0 | 65 | 20 | 1.36(0.80,2.30) | 65 | 18 | 1.40(0.80,2.45) |
| WHR at diagnosis | ||||||
| <0.80 | 130 | 33 | 1.00 | 130 | 27 | 1.00 |
| 0.80- | 115 | 23 | 0.71(0.41,1.25) | 115 | 23 | 0.92(0.51,1.65) |
| 0.83- | 134 | 28 | 0.66(0.39,1.13) | 134 | 23 | 0.67(0.37,1.22) |
| ≥0.87 | 139 | 44 | 0.93(0.56,1.54) | 139 | 39 | 1.11(0.64,1.91) |
| P for trend | 0.89 | 0.83 | ||||
a
Adjusted for age at diagnosis (continuous variable), education (<high school, high school, >high school), Charlson comorbidity index (0, ≥ 1), menopausal status at baseline (yes, no),exercise participation at baseline (yes, no), type of surgery received, chemotherapy (yes, no), radiotherapy (yes, no), and TNM stage (I, II, III, unknown)