Table 1.
Patient characteristics N=216
| Parameter | Number (%); Median [range] | |
|---|---|---|
| Age (years) | 66 [20–90] | |
| White Blood Cell Count (x 109/L) | 3.1 [0.7–106] | |
| Absolute Neutrophil Count (x 109/L) | 1.2 [0.1–40] | |
| Hemoglobin (g/dL) | 9.6 [5.7–14.7] | |
| Platelets (x 109/L) | 54 [9–987] | |
| Bone marrow blasts (%) | 7 [0–26] | |
| Prior malignancy | 116 (44) | |
| Prior chemotherapy | 92 (43) | |
| Prior radiotherapy | 56 (26) | |
| Cytogenetics13 | Very good | 5 (2) |
| Good | 9 (4) | |
| Intermediate | 48 (22) | |
| Poor | 36 (17) | |
| Very poor | 118 (55) | |
| WHO | RA | 24 (11) |
| RARS | 9 (4) | |
| RCMD | 19 (9) | |
| RAEB | 133 (62) | |
| MDS-U | 8 (4) | |
| CMML | 23 (10) | |
| IPSS | Low | 7 (3) |
| Intermediate-1 | 41 (19) | |
| Intermediate-2 | 107 (50) | |
| High | 61 (28) | |
| R-IPSS | Very low | 5 (2) |
| Low | 14 (6) | |
| Intermediate | 22 (10) | |
| High | 61 (28) | |
| Very high | 114 (54) | |
| MDGSS | Low | 18 (8) |
| Intermediate-1 | 33 (15) | |
| Intermediate-2 | 57 (26) | |
| High | 108 (51) | |
| Type of HMA | Azacitidine | 67 (31) |
| Decitabine | 149 (69) |