Table 2. Imaging characteristics prior to neoadjuvant chemotherapy.
Imaging characteristics at MRI and PET/CT plotted versus the pathological complete response (pCRmic) and non-pCRmic of tumors to neoadjuvant chemotherapy. LD initial = Largest tumor diameter on initial enhancement. LD late = Largest tumor diameter on late enhancement. SUV-max = Maximum standardized uptake value.
Characteristic | Overall | pCRmic | Non-pCRmic | p-value |
---|---|---|---|---|
MRI baseline; curve type | 0.212 | |||
Persisting | 0 | 0 | 0 | |
Plateau | 81 | 30 | 51 | |
Wash-out | 107 | 47 | 60 | |
MRI baseline; tumor size | ||||
LD initial (mm); mean (sd) | 47 (24) | 46 (23) | 47 (25) | 0.691 |
LD late (mm); mean (sd) | 39 (21) | 38 (18) | 40 (22) | 0.608 |
PET/CT baseline; SUV-max | ||||
SUV-max tumor; mean (sd) | 9.1 (6.0) | 10.3 (7.2) | 8.2 (4.7) | 0.029 |
SUV-max lymph node; mean (sd) | 5.0 (5.1) | 5.7 (5.3) | 4.5 (4.8) | 0.056 |