Table 3. Imaging characteristics during NAC.

Relative change (Δ) of largest tumor diameter on initial (LD initial) and late (LD late) enhancement on MRI ([LD interim–LD baseline / LD baseline] x 100%) and relative change of the maximum standardized uptake value (SUV-max) on PET/CT ([SUV-max interim–SUV-max baseline / SUV-max baseline x 100%] plotted versus pathological complete response (pCRmic) after NAC.

Characteristic	Overall	pCRmic	Non-pCRmic	p-value
MRI Δ
LD initial Δ (%); median (sd)	-42 (34)	-66 (33)	-26 (24)	<0.001
LD late Δ(%); median (sd)	-58 (38)	-82 (28)	-42 (35)	<0.001
PET/CT Δ
SUV-max tumor Δ (%); median (sd)	-53 (27)	-67 (17)	-43 (28)	<0.001
SUV-max lymph node Δ (%); median (sd)	-65 (32)	-74 (31)	-57 (31)	0.001