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. 2017 May 22;12(5):e0177762. doi: 10.1371/journal.pone.0177762

Table 5. Annual cost estimation for prevention, management and treatment of cervical lesions, cancer and genital warts expressed in $ 2015.

Parameter Prevalence 2015 Cost per item Base case cost Range
Number $ 2015 $ 2015 Lower (-50%) Higher (+50)
Screening
Pap smear 8 229 22 180 301 90 150 270 451
Total VIA screened 11 248 53 601 050 300 525 901 576
Biopsy 532 158 83 859 41 929 125 788
20 009 865 210 432 605 1 297 815
Diagnosed cervical lesions
Treatment with LEEP 309 2 049 633 195 316 598 949 793
VIA positive treated with cryotherapy 1 408 96 169 647 84 823 254 470
Follow up of LSIL with Pap smear 6 months later and antibiotics (3 drugs) 12 862 52 664 995 332 497 997 492
Treatment of HSIL with hysterectomy during anesthesia 1 917 3 941 7 554 366 3 777 183 11 331 549
16 496 9 022 203 4 511 102 13 533 305
Diagnosed with cervical cancer
FIGO I-Ib1 22 6 405 140 899 70 450 211 349
FIGO Ib2-II 22 25 527 561 601 280 800 842 401
FIGO III 110 24 992 2 749 172 1 374 586 4 123 759
FIGO IV 66 23 923 1 578 905 789 453 2 368 358
220 5 030 578 2 515 289 7 545 867
Genital warts
Wart removal with cauterization 116 552 63 997 31 999 95 996
Wart removal with Podophyllotoxin and antibiotics 5 995 161 966 720 483 360 1 450 080
6 111 1 030 717 515 359 1 546 076
Total 42 836 15 948 708 7 974 354 23 923 062