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. 2017 May 22;12(5):e0177694. doi: 10.1371/journal.pone.0177694

Fig 3. Autophagy inhibitor facilitates the sensitivity of Ge in TNBC xenografts in vivo.

Fig 3

MDA-MB-468 xenograft tumor was established and treated as follows: DMSO, 3-MA (1.0 mg/kg), Baf.A (1.0 mg/kg), Ge (100 mg/kg), Ge (100 mg/kg) +3-MA (1.0 mg/kg) and Ge (100 mg/kg) +Baf.A (1.0 mg/kg). 3-MA and Baf.A were injected intratumorally, Ge was administered via oral gavage. Tumor growth curves (A), tumor weight (B), tumor image (C), and nude mouse image (D) with different treatment were detected. The results are shown as means ± SD; *p < 0.05.