Table 2.

Criteria for molecular diagnosis. ⁸

Molecular diagnosis	Criteria
Benign nonmucinous	(1) DNA quantity/quality low to moderate; AND
	(2) K‐ras gene point mutation not present; AND
	(3) LOH, <2 genomic loci present
Benign mucinous	(1) DNA quantity/quality: high; OR
	(2) K‐ras gene point mutation present; OR
	(3) LOH, >2 genomic loci present.
Malignant (in situ or invasive carcinoma)	(1) K‐ras gene point mutation, high amplitude (>75°%); OR
	(2) ≥2 more LOH, high amplitude (>75%)

LOH = loss of heterozygosity.