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. 2017 May 12;12:3681–3695. doi: 10.2147/IJN.S134005

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© 2017 Yang et al. This work is published and licensed by Dove Medical Press Limited

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Characterization of HCPT-NSps.

Notes: (A) The particle size distribution of unhomogenized and homogenized HCPT-NSps determined by dynamic light scattering. The average particle size of unhomogenized HCPT-NSps was 170.15±0.3 nm with PDI value being 0.14±0.01, while the homogenized nanosuspensions had smaller size of 92.90±0.2 nm and a little higher PDI value of 0.16±0.01. (B) The micrograph of HCPT-NSps observed by transmission electron microscopy. The small dark punctated spots observed are due to phosphotungstic acid staining.

Abbreviations: HCPT, 10-hydroxycamptothecin; NSps, nanosuspensions; PDI, polydispersity index.