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. 2017 May 12;12:3681–3695. doi: 10.2147/IJN.S134005

Figure 8.

Figure 8

H&E staining of tumor paraffin sections post-HCPT injections.

Notes: (A) Blank control, (B) HCPT injections (5 mg/kg), and (C) HCPT-NSps (5 mg/kg). Normal saline-injected tumors were used as control and no pathological changes were observed. Tumor cells subjected to HCPT injections were slightly damaged, but no significant fission changes were observed. However, massive cellular death was detected after treatment with HCPT-NSps, and only a small population of tumor cells was normal. Magnification of all the pictures is 400×.

Abbreviations: HCPT, 10-hydroxycamptothecin; NSps, nanosuspensions; H&E staining, hematoxylin and eosin staining.