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Change in particle size of 7-ethyl-10-hydroxycamptothecin nanosuspensions reconstituted after storage in the form of lyophilized powder at different times (mean ± SD, n=3)
| Time (day) | 0 | 20 | 40 | 80 | 120 | 180 |
|---|---|---|---|---|---|---|
| Size (nm) | 137.1±0.4 | 139.0±0.4 | 134.5±0.2 | 137.0±0.4 | 135.1±0.5 | 137.4±0.4 |
| PDI | 0.14±0.04 | 0.18±0.02 | 0.17±0.03 | 0.11±0.02 | 0.19±0.04 | 0.19±0.02 |
Notes: All values are presented as mean ± SD; n=3.
Abbreviations: SD, standard deviation; PDI, polydispersity index.
