Table S5.

Linear multivariate regression analysis: association between annual change in SGRQ total-score and exacerbation frequency adjusted for sex, age, augmentation therapy and occupational dust exposure

Variable	Unstandardized coefficient, B	Standardized coefficient, β	95% CI	P-value
Exacerbation frequency in follow-up period	0.68	0.15	0.15 to 1.20	0.011
Sex, female	−0.43	−0.05	−1.56 to 0.69	0.449
Age (years)	0.03	0.07	−0.02 to 0.08	0.233
Augmentation therapy	−1.21	−0.11	−2.59 to 0.16	0.082
Occupational dust exposure	0.12	0.01	−1.00 to 1.24	0.830
Dependent variable: ΔSGRQ total-score/year

Abbreviations: CI, confidence intervals; SGRQ, St George’s Respiratory Questionnaire.