Table S1.

Annualized exacerbation rates for budesonide/formoterol and formoterol for all patients

Study month	Annualized exacerbation rates
	All patients, n=2,345
	BUD/FOR	95% CI	FOR	95% CI
1	0.60	0.48–0.84	1.20	0.96–1.44
2	0.60	0.54–0.72	1.20	1.02–1.32
3	0.60	0.52–0.72	1.12	1.0–1.24
4	0.60	0.54–0.69	1.11	0.99–1.23
5	0.62	0.58–0.72	1.06	0.98–1.17
6	0.66	0.60–0.74	1.04	0.96–1.14
7	0.67	0.62–0.74	0.99	0.99–1.06
8	0.68	0.62–0.74	0.95	0.87–1.02
9	0.68	0.63–0.74	0.93	0.93–1.01
10	0.66	0.61–0.72	0.94	0.86–.996
11	0.65	0.61–0.72	0.91	0.85–0.98
12	0.63	0.58–0.68	0.86	0.80–0.92

Abbreviations: BUD, budesonide; CI, confidential interval; FOR, formoterol.