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Adverse events with metformin immediate release and metformin extended release.
Notes: Metformin IR dosage: 2,000±1,000 mg/day; metformin XR dosage: 1,000±500 mg/day. *P<0.05 vs 3 months with IR. **P<0.01 vs 3 months with IR.
Abbreviations: IR, immediate release; XR, extended release.
