Table 4.

Factors associated with increased risk of HCC based on interpretation of recently published risk prediction models

Increased risk of HCC
General risk factors
Age, gender, and family history
Etiology of liver disease
Alcohol and diabetes +/− markers of insulin resistance
AFP
Hepatitis C virus (HCV)
SVR
Modality of treatment (awaits further studies)
Hepatitis B virus (HBV)
DNA replication if any
Non-cirrhotic
Markers of fibrosis
Cirrhotic
Platelet count
Child–Pugh score (if decompensated)

Abbreviations: AFP, alpha-fetoprotein; HCC, hepatocellular carcinoma; SVR, sustained virologic response.