Table 3. Summary of agents capable of inducing hypermutation and types of antibiotic resistance induced.

Drugs and Chemicals that can Induce the SOS Response, by recA Assays	Drugs and Chemicals that can Induce Hypermutation			Drugs to Which Resistance Can be Induced
		Quantitative	Qualitative
ciprofloxacin	ciprofloxacin	√	√	rifampin, trimethoprim, chloramphenicol
Pyrimidine analogs
zidovudine (AZT)	zidovudine	√		rifampin, chloramphenicol
5-fluorouracil
5-azacytidine
Purine analogs
6-mercaptopurine	6-mercaptopurine		√	rifampin
didanosine, ddI
arsenic trioxide, As2O3	arsenic trioxide		√	rifampin, chloramphenicol
paraquat	paraquat		√	rifampin