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. Author manuscript; available in PMC: 2017 May 22.
Published in final edited form as: Virus Res. 2008 Sep 9;139(2):230–239. doi: 10.1016/j.virusres.2008.07.016

Figure 2.

Figure 2

Sequence and predicted secondary structure of 5′ and 3′ terminal sequences of DENV2. On top, t structural elements located at the 5′ end of the genome: stem loop A (SLA), stem loop B (SLB), and capsid region hairpin (cHP) are shown linked by a dash line, representing the viral genome, to the 3′stem loop (3′SL). The bottom structure shows the changes upon hybridization of the complementary sequences, which results in RNA cyclization. Note that the predicted SLA and cHP are maintained while the SLB and the 3′SL changed after 5′-3′UAR and 5′-3′CS interaction.