Table 3.

Mean between-subject coefficients of variation (BS-CV; %) for participants’ parameter estimates (BP_ND/SUV/V_T) obtained with the six different methods (12 variants).

Method	2kbv	4kbv	Logan’s graphical analysis	Logan’s graphical analysis	SA	SA	SUV (30.5–60.5 min)	SUV (60.5–90.5 min)	SRTM brainstem	SRTM2 brainstem	SRTM cerebellum	SRTM2 cerebellum
Parameter	VT	VT	VT	VT	VT	VT	SUV	SUV	BPND	BPND	BPND	BPND
Regional/Voxelwise	Regional	Regional	Regional	Voxelwise	Regional	Voxelwise	Voxelwise	Voxelwise	Regional	Voxelwise	Regional	Voxelwise
ACG	15	9	12	12	10	10	16	20	5	5	8	8
Fusiform gyrus	15	26	12	12	14	14	14	19	5	6	7	8
Hippocampus	15	9	10	11	12	11	13	18	8	9	8	11
Inferior frontal gyrus	12	20	10	10	15	12	18	22	8	8	9	10
Insula	14	11	10	10	10	10	14	18	6	6	7	8
Occipital lobes	11	18	9	10	14	10	19	21	7	7	9	9
Median	15	15	10	11	13	11	15	20	7	7	8	9
(iqr)	(13–15)	(10–20)	(10–12)	(10–12)	(11–14)	(10–12)	(14–18)	(18–21)	(5–8)	(6–8)	(7–9)	(8–10)

2/4kbv=2/4 rate constant compartmental models with variable blood volume, ACG=Anterior cingulate gyrus, BP_ND=Binding potential relative to non-displaceable binding, iqr=Interquartile range, SUV=Standardised uptake value, ROI=Region-of-interest, SA=Spectral analysis, SRTM=Simplified reference tissue model, t-rt=test-retest, V_T=Volume-of-distribution.