Table 4.

Intraclass Correlation Coefficients (ICCs) for participants’ parameter estimates (BP_ND/SUV/V_T) obtained with the six different methods (12 variants).

Method	2kbv	4kbv	Logan’s graphical analysis	Logan’s graphical analysis	SA	SA	SUV (30.5–60.5 min)	SUV (60.5–90.5 min)	SRTM brainstem	SRTM2 brainstem	SRTM cerebellum	SRTM2 cerebellum
Parameter	VT	VT	VT	VT	VT	VT	SUV	SUV	BPND	BPND	BPND	BPND
Regional/Voxelwise	Regional	Regional	Regional	Voxelwise	Regional	Voxelwise	Voxelwise	Voxelwise	Regional	Voxelwise	Regional	Voxelwise
ACG	−0.24	0.64	0.08	0.00	0.32	0.91	0.59	0.62	−0.33	−0.18	0.59	0.66
Fusiform gyrus	−0.38	0.45	−0.08	−0.12	0.60	0.71	0.67	0.65	0.22	0.27	0.68	0.64
Hippocampus	−0.52	0.89	−0.07	−0.10	0.35	0.89	0.72	0.72	0.77	0.85	0.95	0.93
Inferior frontal gyrus	−0.41	−0.01	−0.01	−0.02	0.40	0.88	0.76	0.75	0.63	0.66	0.87	0.87
Insula	−0.55	0.51	−0.21	−0.22	−0.73	0.90	0.60	0.63	0.22	0.34	0.74	0.84
Occipital lobes	−0.65	0.36	−0.30	−0.30	−0.18	0.59	0.72	0.68	0.46	0.50	0.63	0.81
Median	−0.47	0.48	−0.08	−0.11	0.34	0.89	0.70	0.67	0.34	0.42	0.71	0.83
(iqr)	(−0.54 to −0.39)	(−0.38 to 0.61)	(−0.18 to −0.03)	(−0.20 to −0.04)	(−0.06 to 0.39)	(0.75–0.90)	(0.62–0.72)	(0.64–0.71)	(0.22–0.59)	(0.29–0.62)	(0.64–0.84)	(0.70–0.86)
Hippocampus /Occipital lobes	1.7	1.9	1.8	1.8	1.8	2.2	1.9	2.5	2.1	1.9	3.2	2.8

2/4kbv=2/4 rate constant compartmental models with variable blood volume, ACG=Anterior cingulate gyrus, BP_ND=Binding potential relative to non-displaceable binding, iqr=Interquartile range, SUV=Standardised uptake value, ROI=Region-of-interest, SA=Spectral analysis, SRTM=Simplified reference tissue model, t-rt=test-retest, V_T=Volume-of-distribution.