Table 1.
Selected post-genomic studies of clade I nematodes [2].
| Species | Clade [4] | Host | Life stage(s) | Platform / Method | Accession | Reference |
|---|---|---|---|---|---|---|
| mRNAs | ||||||
| Trichinella spiralis | 2A | Human, Swine | newborn larvae, muscle larvae, adult | Illumina Solexa | GEO: GSE39151 | [21] |
| newborn larvae, muscle larvae, adult | Illumina HiSeq2000 | GEO: GSE39328 | [22] | |||
| Trichuris muris | 2A | Mouse | L2, L3, adult female, adult male, female and male tissues | Illumina HiSeq2000 | AE: E-ERAD-125 | [14] |
| Trichuris suis | 2A | Swine | adult | Illumina GAII | n/a | [31] |
| L1/L2, L3, L4, adult female, adult male, female and male tissues | Illumina HiSeq2000 | ENA: PRJNA208415 | [15] | |||
| Trichuris trichiura | 2A | Human | adult | Ion Torrent Ion 318 | ENA: PRJEB12315 | [19] |
| Small RNAs | ||||||
| Trichinella spiralis | 2A | Human, Swine | newborn larvae, muscle larvae, adult | Illumina Solexa | n/a | [24] |
| L1 (muscle), adult | Illumina MiSeq | GEO: GSE56651 | [23] | |||
| Trichuris suis | 2A | Swine | L1/L2, L3, L4, adult female, adult male, adult female and male tissues | Illumina GAII | ENA: PRJNA208415 | [15] |
| Methylation | ||||||
| Trichinella spiralis | 2A | Human, Swine | newborn larvae, muscle larvae, adult | Illumina HiSeq2000 | GEO: GSE39328 | [22] |
| Proteins | ||||||
| Trichinella spiralis | 2A | Human, Swine | ESP from muscle larvae | PB MALDI-TOF-TOF, MS/MS | [27] | |
| ESP from muscle larvae | AB Sciex 4800 MALDI-TOF/TOF-MS | [25] | ||||
| surface protein from muscle larvae | AB Sciex 4800 MALDI-TOF MS | [28] | ||||
| adult somatic proteins | AB Sciex 4800 MALDI-TOF/TOF-MS | [29] | ||||
| surface protein from muscle and intestinal infective larvae | n/a | [30] | ||||
| Trichuris trichiura | 2A | Human | adult somatic extract | W Micromass Q-TOF micro MS | [18] | |
Abbreviations: Applied Biosystems (AB); European Bioinformatics Institute (EBI); EBI ArrayExpress (AE); EBI European Nucleotide Archive (ENA); excretory/secretory products (ESP); mass spectrometer (MS); matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF); National Center for Biotechnology Information (NCBI); NCBI Gene Expression Omnibus (GEO); PerSpective Biosystems (PB); Waters (W)