Table 1. Correlation of clinical factors and PAV change in CER-001 patients.

Clinical variables	β coefficient (95% CI)	P value
Univariate analysis
Age	0.05 (−0.15 to 0.26)	0.40
Female	−0.03 (−0.27 to 0.22)	0.54
Hypertension	0.01 (−0.35 to 0.38)	0.97
Hypercholesterolemia	0.03 (−0.27 to 0.28)	0.60
Diabetes	−0.01 (−0.36 to 0.33)	0.97
Body mass index	0.05 (−0.15 to 0.20)	0.33
Baseline PAV	−0.10 (−0.12 to −0.07)	0.002
Triglyceride
Baseline value	−0.05 (−0.21 to 0.11)	0.38
Percent change	0.06 (−0.08 to 0.20)	0.25
Total cholesterol
Baseline value	−0.05 (−0.25 to 0.16)	0.40
Percent change	−0.01 (−0.29 to 0.32)	0.86
Glycated hemoglobin
Baseline value	−0.02 (−0.31 to 0.27)	0.69
Absolute change	−0.40 (−0.52 to −0.28)	0.01
hs-CRP
Baseline value	−0.02 (−0.30 to 0.26)	0.66
Percent change	−0.11 (−0.22 to 0.02)	0.06
Systolic blood pressure
Baseline value	−0.04 (−0.26 to 0.09)	0.44
Percent change	−0.02 (−0.31 to 0.27)	0.69
Diastolic blood pressure
Baseline value	0.01 (−0.29 to 0.32)	0.84
Percent change	−0.08 (−0.22 to 0.04)	0.17
Multivariate analysis
Age	0.01 (−0.28 to 0.31)	0.45
Female	−0.29 (−0.47 to 0.08)	0.39
Baseline PAV	−0.08 (−0.11 to −0.05)	0.006
Absolute change in glycated hemoglobin	−0.39 (−0.56 to −0.22)	0.03
Percent change in hs-CRP	−0.001 (−0.02 to 0.01)	0.10

CI, confidence interval; hs-CRP, high-sensitivity C-reactive protein, PAV, percent atheroma volume.