Figure 6.

Stromal PDGFRα activation increases growth of Met1 cells in the mammary fat pad. A, Representative images and tumor volume quantification of Met1 mammary tumors arising in orthotopically injected Fsp-cre;Pdgfra^ki/+ and littermate controls (Scale bar – 5 mm). Representative images and quantification of B. percent KI67 positive nuclei, C, CD31 mean vessel size, and D, HABP signal intensity within Met1 tumor sections from Fsp-cre;Pdgfra^ki/+ mice and controls (Control = 10 tumors, Fsp-cre;Pdgfra^ki/+ = 8 tumors; ≥5 images per tumor; Scale bars – 100 μm).