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. 2017 May 22;7:2231. doi: 10.1038/s41598-017-02568-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cell cycle arrest induced by T-2 toxin and/or DON. (a) C28/I2, L-02, and HK-2 cells were exposed to T-2 toxin (10 ng/ml) or DON (800 ng/ml), alone or in combination, for 24 h. and cell cycle phase distribution was analyzed by flow cytometry. Cell cycle phase distribution was quantified as the percentage of total cells in C28/I2 (b), L-02 (c), and HK-2 (d) cells. Data are represented as the mean ± SD from three independent experiments; *P < 0.05 indicates significance versus untreated control values.