Table 7.
Identification of HLA class II epitopes and HLA-epitope docking results
| Toxin | HLA type | Start–end | Epitope* | Binding score | Docking binding energy (kcal/mol) |
|---|---|---|---|---|---|
| Stx1 | HLADRB5*01:01 1 | 187–201 | TAEALRFRQIQRGFR | 0.11 | −873.6 |
| HLADPA1*01:03/DPB1*02:01 | 151–165 | QINRHSLTTSYLDLM | 0.28 | −528.9 | |
| HLADQA1*05:01/DQB1*02:01 | 179–193 | AMLRFVTVTAEALRF | 0.76 | −542.6 | |
| Stx2 | HLADRB3*01:01 | 296–310 | TLWESNTAAAFLNRK | 0.01 | −807.6 |
| HLADPA1*01/DPB1*04:01 | 109–123 | NTFYRFSDFTHISVP | 0.15 | −463.4 | |
| HLADQA1*05:01/DQB1*02:01 | 179–193 | AVLRFVTVTAEALRF | 0.74 | −548.1 |