Fig. 5.

Autocrine IL-10 production causes increased ROS type I latency BL cells. The EBV-positive Akata cells were treated with purified rat anti-human IL-10 Ab (Pharmingen) at a concentration of 10 μg/ml. Normal rat IgG isotype controls were used. After 72 h, the cells were harvested and DCF fluorescence was monitored by flow cytometry. IL-10 blockade results in significant decrease in ROS production.