Table 1. Clinical illness in Tg(PG14) mice with different Bax genotypes.
Tg(PG14)/Bax+/+† | Tg(PG14)/Bax+/- | Tg(PG14)/Bax-/- | |
---|---|---|---|
Age at onset | 235 ± 10 (61) | 240 ± 28 (13) | 255 ± 26 (5) |
Age at death | 371 ± 21 (42) | 353 ± 25 (6) | 332 ± 24 (6) |
Duration of illness | 154 ± 14 (35) | 124 ± 28 (4) | 113 ± 25 (3) |
Entries show the mean number of days ± SEM. The number of animals in each group is given in parentheses. The PG14 transgene array was hemizygous.
Data are from ref. 5