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. 2017 May 23;10:158. doi: 10.3389/fnmol.2017.00158

Table 1.

Summary of dose-response analysis data for α2, α2β, α2R323L and α2R323Lβ Glycine receptors (GlyRs).

α2 α2β α2R323L α2R323Lβ
EC50 μM 46.6 ± 6.7 90.3 ± 14.6 67.9 ± 13.4 143.0 ± 12.9*
Hill slope 2.2 ± 0.1 2.1 ± 0.1 2.1 ± 0.2 2.0 ± 0.3
Imax (nA) 1.6 ± 0.2 2.1 ± 0.3 1.5 ± 0.4 1.7 ± 0.2
n 12 11 9 13

Statistical comparisons of α2R323L and α2R323Lβ were made relative to α2 and α2β GlyRs, respectively, via an unpaired Student’s t-test. *p < 0.05.