Table 4.
Single-channel activation parameters of α2β and α2R323Lβ receptors.
Opening probabilities (Po) | Mean duration of active periods (ms) | |||
---|---|---|---|---|
Channel | 100 μM glycine | 3 mM glycine | 100 μM glycine | 3 mM glycine |
α2β | 0.73# | 0.76 ± 0.02 | 165 ± 21 | 242 ± 102 |
α2R323Lβ | 0.85 ± 0.02 | 0.82 ± 0.02 | 277 ± 37* | 360 ± 44 |
Data represent mean (n = 3–4) ± SEM. *p < 0.05, #from n = 2 patches.