Fig. 1.

Distribution of HSV-1 gD and gB receptor expression across a the whole human brain and b telencephalon (data: Allan Brain Atlas). Brain regions (numbered) are 1 hippocampus, Hpc; 2 globus pallidus; 3/4 subthalamus, lateral and geniculate nuclei; 5 ventral thalamus; 6 red nucleus; 7 dentate/fastigial/globose nuclei; 8 superior olivary complex and trigeminal nuclei; 9/10 cuneate/dorsal motor/gracile/vestibular nuclei and corpus callosum; 11 choroid plexus of the lateral ventricle. Asterisk, cerebellum, high expression of PILRA (gB) but low expression of gD receptors. The positive control for region-specific expression was NR3C2 (mineralocorticoid receptor); the housekeeping gene control was glyceraldehyde-3-phosphate dehydrogenase (GAPDH). The lower panel in a gives the plotted mean z scores for PVRL1 + TNFRSF14 + MYH9 (negative scores not presented); the lower panel in b gives the individual z scores for PVRL1, TNFRSF14, and MYH9